Recombinant avian herpesvirus useful in vaccine production
AssigneeSchering-Plough Veterinary Corporation
InventorsMark D. Cochran, Stephanie M. Cook, Martha A. Wild
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Abstract
The present invention provides a novel avian herpesvirus (NAHV) vector and recombinant vaccines made therefrom that are useful to immunize avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease. Methods of immunizing an avian species against Marek's disease, infectious laryngotracheitis and Newcastle disease are also provided.
Claims49
A recombinant avian herpesvirus comprising a Marek's disease virus (MDV) unique short viral genome region, a herpesvirus of turkeys (HVT) unique long viral genome region, and the repeat viral genome regions of the HVT;
- wherein the recombinant avian herpesvirus is capable of being expressed in a host cell.
The recombinant avian herpesvirus comprised by NAHV 295-01 (ATCC Accession number PTA-3451).
A multivalent vaccine for protecting against Marek's disease, infectious laryngotracheitis and Newcastle disease comprising, as a mixture, an effective immunizing amount of a first recombinant avian herpesvirus, comprised by NAHV/ILT 295-149 (ATCC Accession number PTA-3452), an effective immunizing amount of a second recombinant avian herpesvirus, comprised by NAHV/NDV 295-93 (ATCC Accession number PTA-3453), and a suitable carrier.
Dependencies are inferred from the claim text.