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US 6,902,906 B1Granted
Bacteria attenuated by a non-reverting mutation in each of the aroC, ompF and ompC genes, useful as vaccines
AssigneeAcambis Research Limited
InventorSteven Neville Chatfield
Life of this patent
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Abstract
The invention provides a bacterium attenuated by a non-reverting mutation in each of the aroC gene, the ompF gene and the ompC gene. The bacterium is useful as a vaccine. The bacterium may, for example, be an attenuated strain of E. coli useful in vaccination against diarrhoea.
Claims10
An Escherichia coli bacterium attenuated by a non-reverting mutation in each of the aroC gene, the ompF gene and the ompC gene.
Dependencies are inferred from the claim text.