Irradiation device for therapeutic treatment of skin and other ailments

Irradiation device according to claim 1,

• wherein the energy density of one emitted optical pulse is between 0.3-0.8 J/cm2,
• wherein the copy underlined text from claim 21 to here average cw-irradiation intensity of one optical pulse is between 1 mW/cm2-10 W/cm2,
• wherein the radiation source is pulse operable and/or movable in relation to the area to be irradiated,
• wherein the effective pulse length is between 1 μs-500 ms,
• wherein said radiation source has a pulse frequency of 0.01-100 Hz,
• wherein said radiation source is a xenon- or deuterium flashlamp or an overload-pulse operated gallium iodide-doped mercury lamp with a device for the cutting off and/or transformation of the UV parts and other undesired parts of the spectrum within the desired area of the spectrum,
• a phosphor material with UVC-transparent carrier material being arranged in front of the radiation source,
• wherein the transparent carrier material is a fluorescent foil made of silicone elastomer or fluorpolymer doped with anorganic phosphor particles,
• wherein said carrier material or the luminescent foil is doped with at least one of:
• (i) the following phosphors fluorescent in the spectral range of 410-490 nm:
• Sr2P2O7:Eu, Sr5(PO4)3Cl:Eu, BaMg2Al16O27:Eu, CaWO4:Pb;(Sr,Ca,Ba)5(PO4)3Cl:Eu;Sr2P2O7:Sn,(Ba,Ca)5(PO4)3Cl:Eu);
• (ii) the following phosphors fluorescent in the spectral range of 510-560 nm ZnSiO4:Mn;MgAl11O19:Ce,Tb,Mn;YBO3:Tb;LaPO4:Ce,Tb (iii) the following phosphors fluorescent in the spectral range of 610-670 nm Y2O3:Eu;Y(P,V)O4:Eu;
• CaSiO3:Pb,Mn;
• (Sr,Mg)3(PO4)2:Sn;
• 3.5MgO*0.5MgF2*GeO2:Mn,
• wherein the pulsed radiation source has means for operating said radiation source in simmer mode,
• wherein said radiation source is equipped with cooling means for cooling one or the other or both of the area to be irradiated and the fluorescent foil,
• wherein said cooling means is designed as an air cooling means,
• wherein said irradiation device has associated means for the topical or inhalative admission of oxygen,
• wherein the irradiation source has additional emission in the range of one or the other or both of (i) 520-550 nm and (ii) 610-670 nm,
• wherein said radiation source is enclosed by a paraboloid or ellipsoid reflector, and
• wherein the at least one UV emitting radiation source emits a beam of radiation having a beam diameter, and
• wherein the beam diameter of the emitted radiation is at least in one dimension wider than 10 mm and narrower than 100 mm.

Method particularly for the treatment of totally or partially cell mediated inflammations of the skin, connective tissue and the viscera, in particular atopic dermatitis cutaneous T-cell lymphoma, lichen rubber, alopecia areata, systemic lupus erythematodes, psoriasis and scleroderma, including other connective tissue diseases, multiple sclerosis, uveitis, Morbus Crohn and other diseases with an immunological background, including the treatment of infectious diseases such as herpes, papilloma virus, fungus, HIV, prions and burn wounds and disturbed wound healing through bacterial infection comprising the steps of,

• providing at least one radiation source for the irradiation of the treatment area, the emitted wavelength on the treatment area being at least 400 nm and comprising a wavelength range of 400-500 nm, and a phosphor material with UVC-transparent carrier material arranged in front of the radiation source, wherein said UVC-transparent carrier material is a fluorescent foil made of silicone elastomer or fluoropolymer doped with anorganic phosphor particles,
• generating optical pulses of radiation from the radiation source, the generated optical pulses having a peak irradiation intensity and an energy density, the peak irradiation intensity of the generated optical pulses being higher than 0.5 W/cm2 and lower than 100 kW/cm2, the energy density of one emitted optical pulse being between 0.05 and 10 J/cm2, and
• applying the optical pulses to the treatment area.