Preparation of porous silicone rubber for growing cells or living tissue
AssigneeCellon S.A.
InventorsJess Paul Fuller, David Pegg, Robert McLean Bird, Timothy Burgess Clifford, Tony Clayson
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Abstract
A method of making a silicone rubber having a structure adapted for growth of cells or living tissue, which comprises contacting a silicone rubber precursor with a biologically-acceptable sacrificial filler, curing the resultant mixture and removing the sacrificial filler to form a structured silicone rubber. The sacrificial filler is preferably an inorganic salt that has been ground, and the salt is selected from metal halides, metal carbonates and metal bicarbonates.
Claims39
A porous silicone rubber article having a structure adapted for growth of cells or living tissue obtained by a method comprising
- mixing a biologically acceptable sacrificial filler with a silicone rubber precursor,
- curing the resultant mixture at a temperature below 180° C., and
- removing the sacrificial filler by dissolution to form a porous silicone rubber article, said sacrificial filler is an inorganic salt that has been ground, and said inorganic salt is selected from the group consisting of metal halides, metal carbonates and metal bicarbonates.
A method of making a silicone rubber article having a structure adapted for growth of cells or living tissue, which comprises mixing a biologically acceptable sacrificial filler with a silicone rubber precursor, curing the resultant mixture at a temperature below 180° C., and removing the sacrificial filler by dissolution to form a porous silicone rubber, said sacrificial filler is an inorganic salt that has been ground, and said inorganic salt is selected from the group consisting of metal halides, metal carbonates and metal bicarbonates.
Dependencies are inferred from the claim text.