68999, a human ubiquitin carboxyl-terminal hydrolase family member and uses therefor
AssigneeMillennium Pharmaceutical, Inc.
InventorRosana Kapeller-Libermann
Life of this patent
Estimating the term…
Abstract
The invention provides isolated nucleic acids molecules, designated 68999 nucleic acid molecules, which encode ubiquitin carboxyl-terminal hydrolase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 68999 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 68999 gene has been introduced or disrupted. The invention still further provides isolated 68999 proteins, fusion proteins, antigenic peptides and anti-68999 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
Claims9
An isolated nucleic acid molecule selected from the group consisting of:
- a. a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:1;
- b. a nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:3;
- and
- c. a nucleic acid molecule which encodes a polypeptide comprising the amino acid sequence of SEQ ID NO:2.
Dependencies are inferred from the claim text.