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US 6,899,850 B2Granted
Method and basket apparatus for transporting biological samples
AssigneeBecton, Dickinson and Company
InventorsBruce C. Haywood, Jamieson W. M. Crawford, Bradley M. Wilkinson
Life of this patent
Estimating the term…
Abstract
A container assembly for storing and stabilizing a biological sample includes a container, a closure cap and a sample holder coupled to the closure cap and removably received in the container. The sample holder can be a basket-like device coupled to an inner face of the cap and includes a central cavity for receiving the sample and immersing the sample in the reagent in the container. The closure cap includes a body member with a dimension to displace a volume of air and reduce the head space to ensure that the sample holder is completely immersed in the reagent. The sample holder has a closure member for closing the open top end of the cavity.
Claims42
A container assembly for storing a biological sample, said assembly comprising:
- a container having a bottom, a side and an open top end, said container having a dimension to contain a volume of a reagent sufficient to treat a biological sample;
- a closure cap for coupling to said open top end of said container;
- and
- a sample holder coupled to said cap and being positioned to be received in said container, said sample holder having an internal cavity with a dimension for receiving a biological sample, said sample holder having a plurality of fluid openings into said cavity to enable free flow of said reagent into said cavity while retaining said biological sample in said cavity, said sample holder having a dimension to fit between said bottom and side of said container and said cap and to immerse said cavity in said reagent, said sample holder including a base member having a width equal to or greater than a width of said internal cavity to displace a predetermined portion of said reagent in said container and to reduce a head space above said reagent in said container and to maintain said internal cavity of said sample holder immersed in said reagent, said cavity of said sample holder having a volume to limit the size of said biological sample to maintain a predetermined ratio of an amount of said biological sample to an amount of said reagent to treat said biological sample.
1 more element
A container assembly for storing a biological sample, said assembly comprising:
- a container having a bottom, a side and an open top end, said container having a dimension to contain a volume of a reagent sufficient to treat a biological sample;
- a closure cap for coupling to said open top end of said container;
- and
- a sample holder coupled to said cap and being positioned to be received in said container, said sample holder having an internal cavity with a dimension for receiving a biological sample, said sample holder having a plurality of fluid openings into said cavity to enable free flow of said reagent into said cavity while retaining said biological sample in said cavity, said sample holder having a dimension to fit between said bottom and side of said container and said cap and to immerse said cavity in said reagent, said cavity of said sample holder having a volume to limit the size of said biological sample, said container having an internal volume and said sample holder having an internal volume, and wherein the ratio of said internal volume of said container and said internal volume of said sample holder is at least 5:1.
1 more element
A container assembly, comprising:
- a container having a bottom, a side and an open top end, and being dimensioned to contain a biological sample treating reagent in a volume sufficient to treat a biological sample;
- a closure cap removably coupled to said container and closing said open top end, said closure cap having an outer face and an inner face;
- a sample holder coupled to said inner face of said cap, said sample holder having a side wall with at least one open area, and an internal cavity for receiving a biological sample, and at least one fluid opening into said cavity, said sample holder having a dimension to fit within said container to completely immerse said cavity in said reagent, said sample holder being positioned with respect to said inner face of said cap to substantially prevent linear movement of said sample holder in said container;
- and
- a body integrally formed with said sample holder and extending from said inner face of said closure cap and having a dimension to displace a portion of said air and reagent in said container to completely immerse said sample holder in said reagent and where said side wall of said sample holder extends axially from said body.
2 more elements
A container assembly for storing a biological sample, said assembly comprising:
- a container having a bottom, a side and an open top end, said container having a dimension to contain a volume of a reagent sufficient to treat a biological sample;
- a closure cap for coupling to said open top end of said container;
- and
- a sample holder coupled to said cap and being positioned to be received in said container, said sample holder having an internal cavity with a dimension for receiving a biological sample, and having a plurality of fluid openings into said cavity to enable free flow of said reagent into said cavity while retaining said biological sample in said cavity, said sample holder having a dimension to fit between said bottom and side of said container and said cap and to immerse said cavity in said reagent, said sample holder further having an annular side wall, a bottom, an open top and an annular base coupled to said closure cap and having an axial length to space said internal cavity from said closure cap.
1 more element
Dependencies are inferred from the claim text.