US 6,893,493 B2 · Preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle

Abstract

The present invention relates to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, and more particularly, to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, which is environment-friendly and advantageous in disintegration and dissolution when used as an enteric coating material, which is prepared by obtaining suitable hydroxypropyl methyl cellulose phthalate (HPMCP) particle through aqueous emulsification process and regulating content of remaining electrolyte through ion exchange process.

Claims7

Dependent claims

A preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle comprising the steps of:

1) emulsifying hydroxypropyl methyl cellulose using an emulsifying agent and NH4OH;
and
2) regulating the remaining electrolyte content to 0-50 mS using ion exchange resin or membrane.

Dependencies are inferred from the claim text.

Facts

Application

10/250,790Filed 22 Nov 2001

Priority

KR 2001-7096615 Nov 2001

Published

US 2005/0000388 A16 Jan 2005

Granted

17 May 2005

Term ends

Not estimatedThe source records don’t support an estimate.

Classification7 codes

C08J 3/16
Powdering or granulating: by coagulating dispersions
A61K 9/2866
Polysaccharides, e.g. gums; Cyclodextrin: cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
C08L 1/32
Cellulose derivatives: cellulose ether-esters
C08J 2301/32
Cellulose derivatives: cellulose ether-esters

Preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle

Life of this patent

Preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle

Life of this patent

Abstract

Claims7