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US 6,890,910 B1Granted
Murd protein and gene of Pseudomonas aeruginosa
AssigneeMerck & Co., Inc.
InventorsMohammed El-Sherbeini, Barbara Azzolina
Life of this patent
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Abstract
This invention provides isolated polynucleotides that encode the MurD protein of Pseudomonas aeruginosa. Purified and isolated MurD recombinant proteins are also provided. Nucleic acid sequences which encode functionally active MurD proteins are described. Assays for the identification of modulators of the of expression of murD and inhibitors of the activity of MurD, are also provided.
Claims5
An isolated and purified polynucleotide selected from the group consisting of:
- (a) a polynucleotide encoding a polypeptide having the amino acid sequence of SEQ ID NO:
- 2, and
- (b) a polynucleotide which is fully complementary to the polynucleotide of (a).
Dependencies are inferred from the claim text.