9H-imidazo[1,2-a]purin-9-one compounds
AssigneeYung Shin Pharmaceutical Ind. Co., Ltd.
InventorsFang Yu Lee, Fang Chen Lee, Chang An Yang, Ma Wei Yong, Xu Ai Wu, Wu Qiu Ye, Xiao Xu Hua
Life of this patent
Estimating the term…
Abstract
Fused tri-heterocyclic compounds of formula: R1 is H or alkyl; R2 is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl; R3 and R4, independently, is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, heterocyclyl, or (CRaRb)mX(CRcRd)nY; in which X is a bond, O, S, or NRe; Y is alkoxy, aryloxy, heteroaryloxy, OC(O)Re, C(O)Re, N(ReRe′), NReC(O)Re′, S(O)2Re, or SRe; each of m and n, independently, is 1, 2, 3, 4, or 5; each of Ra, Rb, Rc, Rd, Re, and Re′, independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl; and R5 is H or halogen.
Claims29
A compound having the following formula:
- wherein
- R1 is H or alkyl;
- R2 is C2-6 alkyl, alkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- R3 is alkyl, alkenyl, cyclyl, heterocyclyl, or (CRaRb)mX(CRcRd)nY;
- in which X is a bond, O, S, or NRe;
- Y is alkoxy, aryloxy, heteroaryloxy, OC(O)Re, C(O)Re, N(ReRe′), NReC(O)Re′, S(O)2Re, or SRe;
- each of m and n, independently, is 1,2,3,4, or 5;
- each of Ra, Rb, Rc, Rd, Re, and Re′, independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- R4 is H, alkyl, alkenyl, cyclyl, heterocyclyl, or (CRaRb)mX(CRcRd)nY;
- in which X is a bond, O, S, or NRe;
- Y is alkoxy, aryloxy, heteroaryloxy, OC(O)Re, C(O)Re, N(ReRe′), NReC(O)Re′, S(O)2Re, or SRe;
- each of m and n, independently, is 1,2,3,4,or 5;
- each of Ra, Rb, Rc, Rd, Re, and Re′, independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- and
- R5 is H or halogen.
A compound having the following formula:
- wherein
- R1 is H or alkyl;
- R2 is C2-6 alkyl, alkenyl, heteroaryl, cyclyl, or heterocyclyl;
- R3 is C2-6 alkyl, alkenyl, cyclyl, heterocyclyl, or (CRaRb)mX(CRcRd)nY;
- R4 is (RaRb)mX(CRcRd)nY in which X is a bond, O, S, or NRe;
- Y is OH;
- each of m and n, independently, is 1,2,3,4, or 5;
- each of Ra, Rb, Rc, Rd, and Re independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- and
- R5 is H or halogen.
A compound having the following formula:
- wherein
- R1 is H or alkyl;
- R2 is H, alkyl, alkenyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- R3 is alkenyl, heterocyclyl, or (CRaRb)mX(CRcRd)nY;
- R4, is (CRaRb)mX(CRcRd)nY, in which X is a bond, O, S, or NRe;
- Y is OH;
- and each of m and n, independently, is 1,2,3,4, or 5;
- each of Ra, Rb, Rc, Rd, Re, and Re′, independently, is H, alkyl, aryl, heteroaryl, cyclyl, or heterocyclyl;
- and R5 is H or halogen.
Dependencies are inferred from the claim text.