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US 6,887,862 B2Granted
Method for improving treatment selectivity and efficacy using intravascular photodynamic therapy
AssigneeMiravant Systems, Inc.
InventorSteven J. Rychnovsky
Life of this patent
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Abstract
A method in which photodynamic therapy is employed to inhibit, stabilize or reduce occlusions within the cardiovascular system by utilizing light within the spectral region of approximately 390 to approximately 610 nm.
Claims59
A method of PDT treatment of cardiovascular indications associated with occlusions of a blood vessel comprising the steps of:
- administering a photosensitizer drug other than psoralen compounds;
- and
- delivering intravascular photoactivating light to the blood vessel at an activation wavelength within the range of about 390 to 610 nm such that the molar extinction coefficient of the photosensitizer drug at the activation wavelength is at least 1000 L cm−1 M−1.
A method of PDT treatment of cardiovascular indications associated with occlusions of a blood vessel comprising the steps of:
- administering a photosensitizer drug;
- and
- delivering a photoactivating light to the blood vessel with an intravascular light delivering device at an activation wavelength within the range of about 440 to 610 nm such that the molar extinction coefficient of said drug at the activation wavelength is at least 1000 L cm−1 M−1.
Dependencies are inferred from the claim text.