Tissue regenerative composition, method of making, and method of use thereof
AssigneeACell, Inc.
InventorAlan R. Spievack
Life of this patent
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Abstract
A matrix, including epithelial basement membrane, for inducing repair of mammalian tissue defects and in vitro cell propagation derived from epithelial tissues of a warm-blooded vertebrate.
Claims52
A matrix, comprising:
- a devitalized mammalian epithelial basement membrane of the urinary bladder and tunica propria immediately subjacent to said basement membrane wherein said matrix induces restoration, remodeling, or repair of a tissue of the urogenital tract when placed in contact with a diseased, damaged or defective tissue of the urogenital tract.
A method for inducing restoration, remodeling, or repair of a tissue of the urogenital tract in a mammal, said method comprising:
- contacting a matrix comprising at least a portion of devitalized mammalian epithelial basement membrane of the urinary bladder with diseased, defective, or damaged tissue of the urogenital tract, wherein said matrix induces restoration, remodeling, or repair of said tissue of the urogenital tract.
A composition, comprising:
- at least a portion of devitalized epithelial basement membrane and tunica propria delaminated from a urinary bladder and shaped to conform to a diseased, damaged, or defective tissue of the urogenital tract.
A matrix for restoring, remodeling, replacing or repairing tissue of the urogenital tract, comprising:
- a devitalized mammalian epithelial basement membrane of the urinary bladder and tunica propria immediately subjacent to said basement membrane.
A method for restoring, remodeling, replacing or repairing a tissue of the urogenital tract in a mammal, said method, comprising:
- applying a matrix comprising at least a portion of devitalized epithelial basement membrane of a mammalian urinary bladder in the mammal having a diseased, defective, or damaged tissue of the urogenital tract.
A composition for restoring, remodeling, replacing, or repairing tissue of the urogenital tract in a mammal, comprising:
- at least a portion of devitalized epithelial basement membrane and tunica propria delaminated from epithelial tissue of a mammalian urogenital tract.
Dependencies are inferred from the claim text.