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US 6,887,493 B2Granted
Multi component controlled release system for oral care, food products, nutraceutical, and beverages
OwnerAdi Shefer, Samuel David Sheferinventors
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OwnerAdi Shefer, Samuel David Sheferinventors
Estimating the term…
The present invention relates to an improved controlled release system that can encapsulate different flavors, sensory markers, and active ingredients, or combinations of flavors, sensory markers and various active ingredients and release multiple active ingredients in a consecutive manner, one after the other. The controlled delivery system of the present invention is substantially free-flowing powder formed of solid hydrophobic nanospheres that are encapsulated in a moisture sensitive microspheres. The flavors, and active ingredients encapsulated in the hydrophobic nanospheres, in the water sensitive microsphere, or in both the nano and the microsphere. The flavors and active ingredients encapsulated in the nanospheres can be the same or different from those encapsulated in the microspheres. The encapsulation of different flavors or active agents in the various components of the system, such as nanospheres and microspheres, provides flavor transition (change in flavor character) during the use of the products. The controlled release system of the present invention enhances the stability and bioavailability of wide range of flavors, sensory markers, and other active ingredients, prolong their residence time in the oral cavity, control their release characteristics, and prolong the sensation of flavors and other sensory markers in the mouth to provide long lasting organoleptic perception or long lasting mouthfeel. The invention further relates oral care, food products, and beverages comprising the controlled release system of the present invention.
A food product comprising a plurality of solid nanospheres formed of a hydrophobic material, said hydrophobic material is selected from the group consisting of carnauba wax, candelilla wax, and mixtures thereof, each of said solid hydrophobic nanospheres encapsulated an effective amount of a first active agent contained therein, said plurality of nanospheres being homogenously dispersed within a moisture sensitive microsphere, said microsphere is formed of a moisture sensitive matrix material, said moisture-sensitive matrix material is selected from the group consisting of water soluble synthetic polymers, water dispersible synthetic polymer, starch derivative, natural gum, polysaccharide, protein, hydrocolloid and mixtures thereof, wherein said microsphere dissolves upon contact with said moisture to provide a burst of said nanospheres or said microsphere swells or softens to slowly release said nanospheres and said nanospheres release said active agent continuously thereafter for an extended period of time.
A hydrated sauce or soup composition comprising a plurality of solid nanospheres formed of a hydrophobic material, said hydrophobic material is selected from the group consisting of carnauba wax, candelilla wax, and mixtures thereof, each of said solid hydrophobic nanospheres encapsulated an effective amount of a first active agent contained therein, said plurality of nanospheres being homogenously dispersed within a moisture sensitive microsphere, said microsphere is formed of a moisture sensitive matrix material, said moisture-sensitive matrix material is selected from the group consisting of water soluble synthetic polymers, water dispersible synthetic polymer, starch derivative, natural gum, polysaccharide, protein, hydrocolloid and mixtures thereof, wherein said microsphere dissolves upon contact with said moisture to provide a burst of said nanospheres or said microsphere swells or softens to slowly release said nanospheres and said nanospheres release said active agent continuously thereafter for an extended period of time.
Dependencies are inferred from the claim text.