Gene therapy vehicle comprising dermal sheath tissue
AssigneesAmanda Reynolds-Jahoda, Colin Albert Buchanan Jahoda
InventorsAmanda Reynolds Jahoda, Colin Albert Buchanan Jahoda
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Abstract
The invention herein described relates to a gene therapy vehicle, comprising dermal sheath tissue and/or cells derived from portions of hair follicles which show pluripotentiality, and which has use in the delivery of therapeutic agents to selected tissues and advantageously has the potential to repair/replace damaged tissue.
Claims33
A therapeutic composition, comprising isolated hair follicle dermal sheath tissue and/or a cell derived therefrom comprising at least one selected gene, or functional fragment thereof, and wherein said at least one selected gene, or functional fragment thereof is delivered to a target site when said dermal sheath tissue is part of a gene therapy vehicle.
A gene therapy vehicle for delivering at least one selected gene, or functional fragment thereof, to a target site wherein said gene therapy vehicle comprises isolated hair follicle dermal sheath tissue and/or a cell derived therefrom.
A gene therapy vehicle for use in delivering a selected gene, or functional fragment thereof, to a given site wherein said gene therapy vehicle comprises hair follicle dermal sheath tissue and/or a cell derived therefrom, which tissue and/or cells comprise heterologous genetic material and which, in vivo, said dermal sheath tissue and/or cell differentiate to provide at least one differentiated tissue type.
Dependencies are inferred from the claim text.