Streptococcus pneumoniae proteins and vaccines
AssigneeMedImmune, LLC
InventorsJohn E. Adamou, Gil H. Choi
Life of this patent
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Abstract
The present invention relates to novel immunogenic polypeptides, and fragments thereof, and vaccines for the prevention and treatment of pneumococcal infection, especially by Streptococcus pneumoniae. The invention also relates to antibodies against the disclosed polypeptides, as well as vaccines containing said polypeptides and methods of disease prevention.
Claims9
An immunogenic composition comprising an isolated polypeptide comprising the amino acid sequence of SEQ ID NO:6 in a pharmaceutically acceptable carrier wherein said polypeptide is present in an amount effective to elicit production of antibodies against Streptococcus pneumoniae when administered to a mammal.
A vaccine comprising an isolated polypeptide comprising the amino acid sequence of SEQ ID NO:6 in a pharmaceutically acceptable carrier wherein said polypeptide is present in an amount effective to elicit production of protective antibodies in a mammal against Streptococcus pneumoniae.
An isolated polypeptide comprising the amino acid sequence of SEQ ID NO:
- 6.
Dependencies are inferred from the claim text.