Formalin-treated human papillomavirus L1 protein vaccine
AssigneeGeorgetown University
InventorsC. Richard Schlegel, A. Bennett Jenson, Shin-je Ghim
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Abstract
Recombinantly produced L1 major capsid proteins which mimic conformational naturalizing epitopes on human and animal papilloma virions including canine and equine papilloma virions are provided. These recombinant proteins are useful as vaccines for conferring protection against papillomavirus infection. Antibodies to the recombinant protein are also provided. Such antibodies are useful in the diagnosis and treatment of viral infection.
Claims8
A vaccine for conferring protection against human papillomavirus (HPV) infection in a human susceptible to human papillomavirus infection which comprises (i) a composition comprising a formalin-treated human papillomavirus L1 protein and (ii) a pharmaceutically-acceptable carrier.
Dependencies are inferred from the claim text.