Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator

#The present invention relates to a multi-purpose, high-functional, alkaline solution composition, a preparation method therefor, and use thereof as an nonspecific immunostimulator. More particularly, the present invention relates to an alkaline solution composition which mostly comprises sodium metasilicate (pentahydrate) and shows nonspecific immunostimulating activities, including antibody production and immune enhancement, by activating immune cells, thereby maximizing vaccination effects versus malignant virus diseases, preparation therefor, and use thereof as an immunostimulator. 2. Description of the Prior Art

#The functionality of alkaline mass in the body has been of great interest since the early 20th century. Extensive research has recently revealed that alkaline mass in the body increases ionization ratios of potassium and sodium to heighten the purification capability of blood, resulting in blood clearance, fatigue-reduction, and aging retardation.

#One alkaline solution composition is disclosed in Korean Pat. No. 128,110, yielded to the present inventor, which comprises 10-18 parts by weight of sodium silicate, 0.1-0.5 parts by weight of sodium hyperoxide, 5-10 parts by weight of potassium carbonate, 1 part by weight of sodium carbonate, 10-18 parts by weight of refined sugar and 0.1-3.0 parts by weight of silver thiosulfate in water. The said composition is now used for the post-treatment of fiber products and the fermentation of feedstuff and in the agricultural industry by virtue of its high far infrared radiation efficiency, antibacterial activity and deodorizing activity. The composition, however, is disadvantageous in that its preparation is complicated and it is difficult to store for a long period of time.

#The above and other objects, features and other advantages of the present invention will be more clearly understood from the following detailed description taken in conjunction with the accompanying drawings, in which:

#FIG. 1 is a graph in which changes in the proportions of porcine CD4+ T lymphocytes in the BARODON®-fed groups and in the control group are plotted against time;

#FIG. 2 is a graph in which changes in the proportions of porcine MHC class II-presenting cells in the BARODON®-fed groups and in the control group are plotted against time;

#The present invention contemplates an NIS based on an alkaline solution composition. This composition comprises sodium metasilicate, borax, sodium thiosulfate, potassium carbonate, refined sugar, and water, optionally sodium chloride, silver thiosulfate and/or sodium molybdate.

#Sodium metasilicate, useful in the present invention, has five crystalline water molecules and comprises silicon dioxide (SiO2) at an amount of 27.5-29.0% and sodium oxide (Na2O) at an amount of 28.5-30.0% with a content error margin less than 2%. This compound is quite stable compared with commercially available liquid sodium silicate. Existing as a white powder or grain, sodium metasilicate is easy to weigh accurately and convenient for long-term storage and transportation. When being dissolved in water, sodium metasilicate is of strong alkalinity. Silicon, like the other constituents of sodium metasilicate, is an essential element for the growth of animals and plants.

#Borax having with ten crystal water molecules has a specific density of 1.715. As a constituent of borax, boron (B) is a trace element in which animals and plants are likely to be deficient. Fruit trees, when soils are insufficient in boron, do not bear well and, if produced, many of their fruits are defective. Generally, borax is used as a bacterium repellent, an insect repellent, a styptic, and a glaze material. When melted together with metals, borax has the property of dissolving the metals. A solution of borax dissolved in water is alkaline with approximately pH 9.5. In the composition of the present invention, the amount of borax is preferably adjusted within the range of 1-15 parts by weight based on 100 parts by weight of sodium metasilicate. For instance, if borax is used at an amount less than 1 part by weight, no effects thereof are exhibited. On the other hand, if the borax content exceeds 15 parts by weight, toxicity may be generated.