Filamentary means for introducing agents into tissue of a living host
AssigneeAderans Research Institute, Inc.
InventorThomas H. Barrows
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AssigneeAderans Research Institute, Inc.
InventorThomas H. Barrows
Estimating the term…
The present invention provides a filamentary structure for the introduction of agents into a living host, comprising a filament comprising a solid core and a porous sheath which coats at least a portion of the solid core. When the filamentary structure is to be permanently implanted into a living host, both the solid core and the porous sheath are bioabsorbable. When the filamentary structure is to be temporarily implanted into the skin of a living host to deliver agents, such as cells, therein, the porous sheath is preferably bioabsorbable but the core need only be biocompatable, not bioabsorabable. The devices and methods of the present invention enable one to regenerate hair follicles, to introduce genetically altered cells or encapsulated cells to a living host transdermally, to regenerate bones, and to deliver drugs transdermally.
A filamentary structure for the introduction of an agent into a living host, comprising a filament comprising a solid core and a porous sheath, and an agent selected from the group consisting of hair follicle cells, genetically engineered cells, encapsulated cells, and cell signaling molecules, wherein the solid core comprises a metal or an alloy and wherein the porous sheath comprises a bioabsorbable sheath polymer which coats at least a portion of the solid core.
A method of making a filamentary structure for introducing an agent into a living host, comprising the steps of:
Dependencies are inferred from the claim text.