Vaccines containing ribavirin and methods of use thereof
AssigneeTripep AB
InventorsMatti Sällberg, Catharina Hultgren
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Abstract
Compositions and methods for enhancing the effect of vaccines in animals, such as domestic, sport, or pet species, and humans are disclosed. More particularly, vaccine compositions comprising ribavirin and an antigen, preferably an antigen that has an epitope present in Hepatitis C virus (HCV), are disclosed for use in treating and preventing disease, preferably HCV infection.
Claims14
An immunogenic composition comprising nucleic acid molecule encoding a viral antigen polypeptide and ribavirin for co-administration thereof.
A method of making an immunogenic composition comprising:
- providing ribavirin;
- providing a nucleic acid that encodes a viral antigen;
- and
- combining said ribavirin and said nucleic acid to formulate said immunogenic composition.
A method of making an immunogenic composition comprising:
- providing ribavirin;
- providing a nucleic acid that encodes a hepatitis antigen;
- and
- combining said ribavirin and said nucleic acid to formulate said immunogenic composition.
A method of making an immunogenic composition comprising:
- providing ribavirin;
- providing a nucleic acid that encodes a hepatitis C antigen;
- and
- combining said ribavirin and said nucleic acid to formulate said immunogenic composition.
A method of making an immunogenic composition comprising:
- providing ribavirin;
- providing a nucleic acid, that encodes a hepatitis C antigen comprising NS3;
- and
- combining said ribavirin and said nucleic acid to formulate said immunogenic composition.
A method of making an immunogenic composition comprising:
- providing ribavirin;
- providing a nucleic acid that encodes a hepatitis C antigen comprising NS4A;
- and
- combining said ribavirin and said nucleic acid to formulate said immunogenic composition.
Dependencies are inferred from the claim text.