Glycine betaine and its use

Method for treating a human at risk to suffer from thrombo-embolic diseases of arterial or venous origin not induced by hyperhomocysteinuria or homocysteinuria, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method for treating a human at risk to suffer from blood coagulation disorders, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as an antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human at risk to suffer from throboses and with hemorrhage risk, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of lysing thrombus in a patient, said method comprising the step of administering a therapeutically effective amount of glycine betaine as lysing agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of counteracting thrombo-embolic effects induced by a contrasting product administered to a human, said method comprising the step of administering a therapeutically effective amount of glycine betaine as counteracting agent against thrombo-embolic effects induced by the administered contrasting agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form, and patches.

A method for lessening the incidence of hemorrhagic side effects in a human associated with the administration of an antithrombotic active agent other than glycine betaine, wherein the method comprises the step of administering an effective amount of glycine betaine as lessening agent of the incidence of hemorrhagic side effects due to the administration of said antithrombotic active agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating thromboses not induced by hyperhomocysteinuria or homocystinuria in a human, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as an antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human suffering from blood coagulation disorders, said method comprising the step of administering a therapeutically effective amount of glycine betaine for reducing the activation of constituents of blood and for reducing the activation of coagulation resulting in the formation of thrombin, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human at risk to suffer from blood coagulation disorders as defined by Virshow, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as an antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, subcutaneous injectable dosage form and patches.

Method of treating a human suffering from thrombin formation, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent for reducing the activation of blood coagulation or thrombin formation, said administering step being carried out by a form selected from the group consisting or an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human suffering of a blood hypercoagulable state as defined by Virchow, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine to said human, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human at risk to suffer of a blood hypercoagulable state as defined by Virchow, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine to said human, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating a human at risk to suffer from blood coagulation activation, said method comprising the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form a subcutaneous injectable dosage form and patches.

Method of threating humans suffering from a disease selected from the group consisting of thrombosis, thrombo-embolic diseases, blood coagulation activation disorders, said humans with risk of undergoing hemorrhage, wherein the method comprises the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of treating humans suffering from thrombin formation, said humans with risk of undergoing hemorrhage, wherein the method comprises the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of threating humans at risk to suffer from a disease selected from the group consisting of thrombosis, thrombo-embolic diseases, blood coagulation activation disorders, said patients with risk of undergoing hemorrhage, wherein the method comprises the step of administering daily a therapeutically effective amount of glycine betaine as antithrombotic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.

Method of lysing thrombus in a human, said method comprising the step of administering a therapeutically effective amount of glycine betaine as a fibrinolytic agent, said administering step being carried out by a form selected from the group consisting of an oral dosage form, a subcutaneous injectable dosage form and patches.