Formulation and manufacturing process for coenzyme Q10 soft gel capsules
AssigneeSoft Gel Technologies, Inc.
InventorsRonald G. Udell, Yousry M. A. Naguib, Siva P. Hari
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Abstract
A soft gelatine capsule formulation for improved manufacturing of Coenzyme Q10, comprising Coenzyme Q10 in a thixatropic gelatine carrier capable of admixing without heating with Coenzyme Q10, and capable of keeping Coenzyme Q10 in suspension at ambient temperature.
Claims18
A soft gel capsule comprising Coenzyme Q10 in combination with an antioxidant in a thixatropic gelatine carrier thereby providing a stable uniform suspension of Coenzyme Q10.
A process of manufacturing a soft gel capsule comprising Coenzyme Q10, said process including:
- (a) heating a thixatropic gelatine carrier to a temperature that liquefies the carrier;
- (b) blending in a container under vacuum the heated thixatropic gelatine carrier, Coenzyme Q10, and Vitamin E;
- (c) cooling the blended mixture to a temperature thereby causing the mixture to be a viscous semi-solid;
- (d) mixing the cooled mixture under a nitrogen blanket;
- and
- (e) encapsulating the mixed, cooled mixture in a soft gel capsule.
A soft gel capsule, prepared by a process comprising the steps of:
- (a) heating a thixatropic gelatine carrier to a temperature that liquefies the carrier;
- (b) blending with the heated thixatropic gelatine carrier, Coenzyme Q10 and Vitamin E;
- (c) cooling the blended mixture to a temperature, thereby causing the mixture to form a viscous semi-solid;
- and
- (e) encapsulating the mixed, cooled mixture in a soft gel capsule.
Dependencies are inferred from the claim text.