Peptides for activation and inhibition of δPKC
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsDaria Mochly-Rosen, Leon E. Chen
Life of this patent
Estimating the term…
Abstract
Peptides able to inhibit or activate the translocation or function of δPKC are identified. Administration of the peptides for protection or enhancement of cell damage due to ischemia is described. Therapeutic methods to reduce damage to cells or to enhance damage to cells due to ischemia are also described, as well as methods for screening test compounds for δPKC-selective agonists and antagonists.
Claims9
A δV1-1 peptide comprising an amino acid sequence that has greater than 80% identity with SEQ ID NO:4 and activity as an antagonist of δPKC.
A peptide consisting of SEQ ID NO:4.
Dependencies are inferred from the claim text.