Human enzymes of the metalloprotease family
AssigneeSolvay Pharmaceuticals GmbH
InventorsWilly Deleersnijder, Rico Wiegers, Michael Weske
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Abstract
This invention relates to newly identified polypeptides which have zinc metalloprotease activities and are referred to as IGS5, and polynucleotides encoding such polypeptides, to their use in therapy and in identifying compounds which may be stimulators and/or inhibitors which are useful in therapy, and to production of such polypeptides and polynucleotides.
Claims22
An isolated polypeptide having a zinc metalloprotease activity and consisting of an amino acid sequence selected from the group consisting of SEQ ID NO:2, SEQ ID NO:4 and SEQ ID NO:6.
An isolated polypeptide having a zinc metalloprotease activity and comprising an amino acid sequence that has a sequence identity of at least 99% when compared to SEQ ID NO:4 or SEQ ID NO:6.
An isolated polypeptide having a zinc metalloprotease activity and comprising an amino acid sequence selected from the group consisting of SEQ ID NO:2, SEQ ID NO:4 and SEQ ID NO:6.
An isolated polypeptide having a zinc metalloprotease activity and comprising an amino acid sequence that has a sequence identity of at least 95% when compared to SEQ ID NO:2.
Dependencies are inferred from the claim text.