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US 6,855,526 B2Granted
Method for making mannitol with Lactobacillus intermedius
AssigneeThe United States of America as represented by the Secretary of Agriculture
InventorBadal C. Saha
Life of this patent
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Abstract
Mannitol is produced in a highly efficient fermentative method using Lactobacillus intermedius NRRL B-30560, or in a biochemical method using mannitol dehydrogenase isolated from this strain. Fructose serves as the primary carbon substrate in both the fermentative and biochemical conversions, but important secondary carbon sources include glucose, maltose, mannose and galactose. Mannitol is useful in the food, pharmaceutical, and medicine industries as a sweet-tasting bodying and texturing agent.
Claims8
A method for producing mannitol comprising:
- a. cultivating the bacterium Lactobacillus intermedius NRRL B-30560 in a fermentation medium containing fructose as the primary carbon source under conditions suitable for the growth of said bacterium;
- b. recovering mannitol from said fermentation medium.
Dependencies are inferred from the claim text.