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US 6,855,495 B1Granted
Toso as a target for drug screening
AssigneeRigel Pharmaceuticals, Inc.
InventorDonald Payan
Life of this patent
Estimating the term…
Abstract
The present invention is directed to methods for identifying novel compositions which modulate the activity of Toso, and the use of such compositions in diagnosis and treatment of disease.
Claims3
A method of modulating apoptosis in a cell in vitro comprising:
- administering to said cell an exogenous compound that binds to a Toso protein of said cell, wherein said Toso protein is encoded by a nucleic acid that hybridizes under high stringency conditions to the nucleic acid sequence depicted in FIG. 1 (SEQ ID NO:
- 1) or its full complement, wherein said binding of the compound to the Toso protein modulates apoptosis in said cell.
Dependencies are inferred from the claim text.