Pharmaceutical composition having prophylactic effects on lamivudine-related disease relapse and drug resistance and methods of using the same

A method for treating patients with liver diseases comprising:

• co-administering to said patients an effective amount of a pharmaceutical composition and lamivudine,
• wherein said pharmaceutical composition comprises aqueous extracts of an entire plant of Herba Hedyotidis diffusae, a rhizome of Rhizoma Bistortae, a rhizome of Rhizoma Polygoni Cuspidati, a ripe fruit of Fructus Schisandrae, a rhizome of Rhizoma Menispermi, a root of Radix Scutellariae, a bovine biliary powder, a tuber of Radix Curcumae, a ripe fruit of Fructus Crataegi, a root of Radix Notoginseng, a rice fruit of Fructus Lycii, a root of Radix Ginseng Rubra, a root of Radix Scorphulariae, a root of Radix Angelicae sinensis, and a root of Radix Astragali;
• and
• wherein said pharmaceutical composition prevents a relapse of the liver diseases after lamivudine is discontinued.