Back to results
US 6,855,318 B1Granted
Multi-mer peptides derived from hepatitis C virus envelope proteins for diagnostic use and vaccination purposes
AssigneeInnogenetics N.V.
InventorsGeert Maertens, Erik Depla
Life of this patent
Estimating the term…
Abstract
Multimer peptides (e.g. 30- to 45-mer peptides) derived from hepatitis C virus envelope proteins reacting with the majority of anti-HCV antibodies present in patient sera are described. The usage of the latter peptides to diagnose, and to vaccinate against, an infection with hepatitis C virus is also disclosed.
Claims29
An isolated HCV E2 envelope peptide as defined by any of SEQ ID NOs:
- 18-36.
An isolated HCV E2 envelope peptide consisting of up to 45 contiguous amino acids wherein an amino acid sequence selected from SEQ ID NOs:
- 18-36 is present in said peptide.
An isolated peptide selected from the group consisting of:
- a peptide of 21 to 27 contiguous amino acids of SEQ ID NO:20 or 30;
- a peptide of 21 to 29 contiguous amino acids of SEQ ID NO:26;
- a peptide of 21 to 30 contiguous amino acids of SEQ ID NO:22 or 35;
- a peptide of 21 to 31 contiguous amino acids of SEQ ID NO:17 or 34;
- a peptide of 21 to 32 contiguous amino acids of SEQ ID NO:31;
- a peptide of 21 to 33 contiguous amino acids of SEQ ID NO:21;
- a peptide of 21 to 34 contiguous amino acids of SEQ ID NO:18;
- a peptide of 21 to 35 contiguous amino acids of SEQ ID NO:32;
- a peptide of 21 to 37 contiguous amino acids of SEQ ID NO:19;
- a peptide of 21 to 41 contiguous amino acids of SEQ ID NO:33;
- a peptide of 21 to 43 contiguous amino acids of SEQ ID NO:23;
- and
- a peptide of 21 to 44 contiguous amino acids of SEQ ID NO:27.
10 more elements
Dependencies are inferred from the claim text.