Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
AssigneeSchering Corporation
InventorsJohannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
Life of this patent
Estimating the term…
Abstract
Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
Claims24
A method for radiodiagnosis and/or radiotherapy of a patient, comprising conducting radiodiagnosis and/or radiotherapy of a patient who has been administered a cascade polymer complex having complex-forming ligands complexing at least five ions of an element of atomic numbers 27, 29, 31, 32, 37-39, 43, 49, 62, 64, 70, 75 or 77, as well as, optionally, cations of inorganic and/or organic bases, amino acids or amino acid amides.
A method for detecting tumors in a patient, comprising conducting MRI-, x-ray- or radio-diagnosis of a patient who has been administered a cascade polymer complex having complex-fanning ligands complexing at least five ions of an element of atomic numbers 21-29, 31, 32, 37-39, 42,43, 44,49 or 57-83, as well as, optionally, cations of inorganic and/or organic bases, amino acids or amino acid amides.
A method for susceptibility imaging comprising imaging a patient by in vivo NMR spectroscopy to whom a susceptibility reagent has been administered, wherein said susceptibility reagent is a cascade polymer complex having complex-forming ligands complexing at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, optionally, cations of inorganic and/or organic bases, amino acids or amino acid amides.
Dependencies are inferred from the claim text.