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AssigneeThe Trustees of Columbia University in the City of New York
InventorsShanta Modak, Trupti A. Gaonkar, Lester Sampath
Estimating the term…
Antimicrobial compositions having synergistic combinations of octoxyglycerin and at least one other antimicrobial agent in formulations which are more effective than prior art compositions without causing increased irritation to the skin of the average user. In certain embodiments, skin irritation may be minimized by low concentrations of antimicrobials and/or the presence of soothing compounds such as zinc. Preferred embodiments include combinations of octoxyglycerin, a quaternary compound, and at least one other antimicrobial agent. Without being bound to any particular theory, it is hypothesized that the unexpected antimicrobial effectiveness of combinations of octoxyglycerin may result from an enhancement of the permeability of microbes to antimicrobials caused by octoxyglycerin.
An antimicrobial composition comprising synergistic effective amounts of octoxyglycerin, a quaternary ammonium compound, and an antimicrobial agent selected from the group consisting of biguanide compound, triclosan, phenoxyethanol, an iodine compound and parachlorometaxylenol.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.05 and 0.2 percent of benzalkonium chloride, and between 0.5 and 4 percent of chlorhexidine digluconate.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of a chlorhexidine compound, and between 1 and 2 percent of miconazole.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of a chlorhexidine compound, and between 0.3 and 1 percent polymixin.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of a chlorhexidine compound, and between 0.1 and 0.5 percent neomycin.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of a chlorhexidine compound, and between 1 and 2 percent silver sulfadiazine.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of chlorhexidine digluconate, and between 1 and 2 percent of miconazole.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of chlorhexidine digluconate, and between 0.3 and 1 percent polymixin.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of chlorhexidine digluconate, and between 0.1 and 0.5 percent neomycin.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.5 and 4 percent of chlorhexidine digluconate, and between 1 and 2 percent silver sulfadiazine.
An antimicrobial composition comprising synergistic effective amounts of between 1 and 5 percent (volume/volume) octoxyglycerin, between 0.05 and 2 percent of chlorhexidine digluconate, between 0.3 and 2 percent of phenoxyethanol, between 0.01 and 0.3 percent of a quaternary ammonium compound, and between 20 and 85 percent of an alcohol elected from the group consisting of ethanol and isopropyl alcohol.
Dependencies are inferred from the claim text.