Loading patent…
AssigneeChiron Corporation
InventorsDouglas J. Jolly, Stephen Chang, James G. Respess, Nicholas J. DePolo, David Chi-Tang Hsu, Carlos E. Ibanez, Judith Greengard, Lee Will
Estimating the term…
Methods are provided for obtaining measurable levels of a protein, nucleic acid molecule, or enzymatic product in a bodily fluid or cells of a human, comprising the step of administering to a human a recombinant retroviral preparation having a titer on HT1080 cells of greater than 105 cfu/ml, wherein the recombinant retroviral preparation is capable of directing the expression of a protein, nucleic acid molecule, or enzyme which generates an enzymatic product, such that measurable levels of the protein, nucleic acid molecule, or enzymatic product may be obtained in the bodily fluid or cells of the human.
A TK-1 retroviral vector which expresses a factor VIII protein.
A retroviral vector which expresses a factor VIII protein, wherein said retroviral vector is selected from the group consisting of pBA-5a, pBA-5b and pBA-5c.
A pBA-9b retroviral vector which expresses a factor VIII protein.
A pBA-8b retroviral vector which expresses a factor VIII protein.
Dependencies are inferred from the claim text.