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US 6,818,396 B1Granted
Process for determination of the activity of a substance using an in vitro functional test
AssigneeProteus S.A.
InventorsJean François Bloch, Daniel Dupret, Fabrice Lefevre, Sandrine Dautel, Jean-Michel Masson
Life of this patent
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Abstract
The invention concerns a method for determining the activity of a substance using a functional test, characterized in that it consists in detecting and/or measuring the variation of a known function corresponding to one or several proteins produced in vitro in the presence and in the absence of said substances or to the substance in the presence or in the absence of one or several proteins produces in vitro.
Claims24
A method of screening a substance able to modify the known function of one or more proteins comprising the steps of:
- (a) producing in vitro said proteins
- (b) measuring and/or detecting variation of the known function in the presence and in the absence of the substance which is screened.
Dependencies are inferred from the claim text.