Dietary food supplement containing natural cyclooxygenase inhibitors and methods for inhibiting pain and inflammation
AssigneesAccess Business Group International LLC, Michigan State University
InventorsMuraleedharan G. Nair, Haibo Wang, David L. Dewitt, David W. Krempin, Dipak K. Mody, Yong Qian, David G. Groh, Audra J. Davies, Mary A. Murray, Robin Dykhouse, Marc Lemay
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Abstract
The present invention describes food supplements that contain one or more fruit extracts useful for pain relief and anti-inflammation. The food supplements may be used to inhibit inflammation mediated by cyclooxygenase and more particularly by cyclooxygenase-2.
Claims15
A method of alleviating or reducing pain in a mammal that comprises administering an effective amount of an anthocyanin extract extracted from an elderberry plant to a mammal that is experiencing pain, wherein the extract comprises a mixture of anthocyanins that include cyanidin-3-glucoside, cyanidin-3,5-diglucoside, cyanidin-3-sambubioside, and cyanidin-3-sambubioside-5-glucoside, whereby the mixture of the anthocyanins comprises at least about 90% of the total extract, and wherein the extract is substantially free of anthocyanidins and the extract provides greater cyclooxygenase 2 (COX-2) inhibitory activity than cyclooxygenase 1 (COX-1) inhibitory activity.
Dependencies are inferred from the claim text.