Gene expression base sequences for therapeutic use and drugs for gene therapy
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsKazuhiro Yuda, Katsuhiko Akiyama, Takeshi Goto, Katsuyuki Hamada
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AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsKazuhiro Yuda, Katsuhiko Akiyama, Takeshi Goto, Katsuyuki Hamada
Estimating the term…
The base sequence for the expression of a therapeutic gene and the medicament for gene therapy are disclosed. There is also disclosed the base sequence for the expression of a therapeutic gene, said sequence being shown in any one of from (a) to (d) and capable of directing the expression of the therapeutic gene specifically to squamous epithelium: (a) the base sequence set forth in SEQ ID NO:1 in the Sequence Listing; (b) the base sequence set forth in SEQ ID NO:18 in the Sequence Listing; (c) the base sequence set forth in SEQ ID NO:17 in the Sequence Listing; and (d) the base sequence set forth in SEQ ID NO:16 in the Sequence Listing. Moreover, there is disclosed the medicament for gene therapy containing a therapeutic gene downstream any of the above-mentioned base sequences, capable of directing the expression of the therapeutic gene specifically to squamous epithelium.
An isolated base sequence for the expression of a therapeutic gene, said sequence comprising any of (a), (b), (c) or (d) below, said base sequence containing the sequence set forth in SEQ ID NO:24, and capable of directing the expression of the therapeutic gene specifically to squamous epithelium:
Dependencies are inferred from the claim text.