Wound healing compositions and methods using tropoelastin and lysyl oxidase
AssigneeMatrix Design
InventorBurt D. Ensley
Life of this patent
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Abstract
The present invention provides compositions and methods for promoting wound healing. The composition comprises virgin monomers of tropoelastin and lysyl oxidase. When the lysyl oxidase comes in contact with the tropoelastin, cross-linking of the tropoelastin monomers will occur to form elastin. Contacting the tropoelastin and lysyl oxidase together and applying the mixture to a wound before substantial cross-linking has occurred promotes wound healing by holding the damaged tissue together, increasing the rate of healing, and decreasing the amount of scarring.
Claims10
A method for promoting healing of a skin wound comprising steps of:
- providing isolated tropoelastin wherein the tropoelastin has not previously been crosslinked and is therefore available for crosslinking, and isolated lysyl oxidase, which components are kept separated from each other;
- and
- applying both said tropoelastin and said lysyl oxidase to a skin wound simultaneously or sequentially, so that said tropoelastin is not crosslinked to itself prior to application to the wound.
A kit comprising tropoelastin wherein the tropoelastin has not previously been crosslinked and is therefore available for crosslinking, and lysyl oxidase in separate compartments.
Dependencies are inferred from the claim text.