Fluorescence detection with increased dynamic range
AssigneeAgilent Technologies, Inc.
InventorJohn F. Corson
Life of this patent
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Abstract
The light detection system includes at least two light detection elements. Each element is responsive to a selected light color in a first mode, and each element has a different sensitivity and is responsive to a single color in a second mode for enhanced dynamic range. A preferred embodiment includes four light detectors for responding to four separate colors or for responding with enhanced dynamic range to two colors. Embodiments are disclosed using a mirror/beam splitter arrangement to switch between modes and an embodiment including dichroic filters serving as fractional beam splitters.
Claims14
An array scanner having a light detection system comprising:
- at least two light detection elements, each element responsive to a selected light color in a first mode, and each element having a different sensitivity within a dynamic range and responsive to a single color in a second mode.
An array scanner having a light detection system comprising:
- four light detection elements, each element responsive to a selected color in a first mode;
- and in a second mode, the four light detectors are grouped in two pairs of detection elements, each element in a pair having a different sensitivity from the other element in the pair for increased dynamic range for detection of a color.
Dependencies are inferred from the claim text.