Preparation of metallocenes carrying a cyclopentadiene comprising a basic donor group
AssigneeUniversity of Leeds
InventorsPatrick Columba McGowan, Margaret Dymphna McGowan
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Abstract
The invention provides a method for the preparation of a metallocene halide salt having at least one cyclopentadiene group substituted by a basic group, the method comprising reacting together a metal halide with a cyclopentadiene substituted by a basic group. In a preferred embodiment, the substituted cyclopentadiene is substituted with an amino group and the metal halide titanium tetrachloride. The invention provides a single step process for the preparation of metallocene derivatives which are useful in the formulation of medicaments and as polymerisation catalyst precursors.
Claims37
A method for the preparation of a metallocene halide salt having at least one cyclopentadiene group substituted by a basic group, said method comprising reacting together a metal halide with a cyclopentadiene substituted by said basic group.
A method for the preparation of a metallocene halide salt having at least one cyclopentadiene group substituted by a basic group, said method comprising reacting together a homoleptic halide with a cyclopentadiene substituted by said basic group.
A method for the preparation of a metallocene halide salt having at least one cyclopentadiene group substituted by a basic group, said method comprising reacting together a metal halide with a cyclopentadiene substituted by said basic group, wherein said substituted cyclopentadiene carries a pendant Lewis base.
Dependencies are inferred from the claim text.