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US 6,806,369 B2Granted
Peptide deformylase inhibitors
AssigneeSmithKline Beecham Corporation
InventorsKelly M. Aubart, Siegfried B. Christensen, IV, Jacques Briand, Maxwell David Cummings
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Abstract
PDF inhibitors and novel methods for their use are provided.
Claims3
A compound according to formula (I):
- wherein:
- X is O;
- n is an integer 1 or 2;
- Ar is an aryl group selected from the group consisting of azaindolyl, pyrazinyl, isoxazolyl, oxazolyl, thiazolyl, isothiazolyl, imidazolyl and isoquinolinyl;
- such that Ar may be optionally substituted with one, two, or three substituents selected from the group consisting of optionally substituted alkyl or cycloalkyl of one to nine carbons, halo, alkoxy of one to nine carbons, hydroxy, amino, hydroxyalkyl of one to nine carbons, alkoxyalkyl, wherein the alkyl and alkylene groups are independently of one to nine carbons, optionally substituted aryl or optionally substituted heteroaryl, carboxy, and alkoxycarbonyl.
2 more elements
Dependencies are inferred from the claim text.