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AssigneeHuman Genome Sciences, Inc.
InventorsSteven M. Ruben, Daniel R. Soppet, Reinhard Ebner, Henrik S. Olsen, Paul E. Young, John M. Greene, Ann M. Ferrie, Guo-Liang Yu, Jian Ni, Craig A. Rosen, Laurie A. Brewer, Fouad Janat
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The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
An isolated polypeptide comprising amino acid residues 2 to 47 of SEQ ID NO:139.
An isolated protein comprising the amino acid sequence of the complete polypeptide encoded by the HBJFE12 cDNA contained in ATCC Deposit No. 209177, excepting the N-terminal methionine.
An isolated polypeptide consisting of at least amino acid residues 19 to 47 of SEQ ID NO:139, wherein said isolated polypeptide is capable of being used to generate or select an antibody that specifically binds amino acid residues 19 to 47 of SEQ ID NO:139.
An isolated protein consisting of at least the secreted portion of the polypeptide encoded by the HBJFE12 cDNA contained in ATCC Deposit No. 209177, wherein said isolated protein is capable of being used to generate or select an antibody that specifically binds the polypeptide encoded by the HBJFE12 cDNA contained in ATCC Deposit No. 209177.
An isolated protein consisting of at least 30 contiguous amino acid residues of amino acid residues 1 to 47 of SEQ ID NO:139, wherein said isolated protein is capable of being used to generate or select an antibody that specifically binds amino acid residues 1 to 47 of SEQ ID NO:139.
An isolated protein consisting of at least 30 contiguous amino acid residues of the complete polypeptide encoded by the HBJFE12 cDNA contained in ATCC Deposit No. 209177, wherein said isolated protein is capable of being used to generate or select an antibody that specifically binds the complete polypeptide encoded by the HBJFE12 cDNA contained in ATCC Deposit No. 209177.
Dependencies are inferred from the claim text.