Use of pheromone compounds having MAP kinase modulating activity
AssigneeDarley Pharmaceuticals LTD
InventorNadav Zamir
Life of this patent
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Abstract
A method of screening pheromone compounds for mitogen-activated protein (MAP) kinase modulating activity and for employing such pheromone compounds in compositions suitable for the prevention or treatment of diseases, conditions, and symptoms thereof benefitting from modulation of MAP kinase activity.
Claims6
A method of treating a warm-blooded animal afflicted with a disease selected from the group consisting of cancer, inflammation, neurodegenerative diseases, neurological diseases, autoimmune diseases, allergy related diseases and hormone related diseases, restenosis, psoriasis, myocardial infarction, wounds and tissue repair and conditions and symptoms thereof that would benefit from modulation of MAP kinase activity, comprising administering to the warm-blooded animal a MAP kinase modulating effective amount of a pheromone compound selected from the group consisting of cis-7-tetradecenal, cis-7-tetradecenol, cis-7-dodecenyl ester, heneicosene-11-one, cis-6-heneicosene-11 -one, cis4-tridecenyl ester, cis4-tridecen-1-yl ester, 2-heptanone, cis-7-tetradecenyl ester, trans-5-decenyl ester, cis-2-methyl-7-octadecene, cis-9-heneicosene, trans-2, cis-13-octadecadienal, 14-methyl-cis-8-hexadecenal, 2-methyl-3-butene-2-ol, trans-10-dodecenol, cis-9-tetradecenol, cis-9-tetradecenyl-formate, cis-9-tetradecenol, trans-3, cis-8, cis-11 -tetradecatrienol, cis-7-tridecenol, cis-9-pentadecenol, cis-9-undecenyl ester, trans-3, cis-7-tetradecadienyl ester, trans-3, cis-8-tetradecadienyl ester, and derivatives and analogs thereof.
Dependencies are inferred from the claim text.