Branched substituted amino derivatives of 3-amino-1-phenyl-1h-[1,2,4]triazol, methods for producing them and pharmaceutical compositions containing them

A compound of formula:

• in which:
• R1 and R2 represent, each independently of the other, a halogen atom;
• a (C1-C5)alkyl;
• a (C1-C5)alkoxy;
• a nitro, trifluoromethyl or cyano group;
• an NRaRb amino group in which Ra and Rb represent, each independently of the other, a hydrogen, a (C1-C3)alkyl or a CO(C1-C3)alkyl;
• or an S—R group in which R represents a hydrogen atom or a (C1-C5)alkyl, it being possible for the sulphur atom to be monooxidized or dioxidized;
• R3 represents hydrogen or is as defined above for R1;
• R4 represents hydrogen;
• a halogen;
• a (C1-C5)alkyl;
• a (C3-C5)cycloalkyl;
• a (C3-C5)cycloalkyl(C1-C2)alkyl;
• or an Rc—X—(C1-C2)alkyl group in which Rc represents hydrogen or a (C1-C3)alkyl and X represents O, S, SO or SO2;
• R5 represents a (C1-C5)alkyl, an alkynyl with 3 to 5 carbon atoms or an alkenyl with 3 to 5 carbon atoms;
• a (C3-C5)cycloalkyl(C1-C3)alkyl;
• or a (C1-C3)alkyl-X—(C0-C3)alkyl in which X represents O, S, SO or SO2;
• R6 represents a —CHR7R8, in which
• R7 represents a phenyl group which can be substituted in the 3-, 4- and 5-positions by one or more Z′ radicals, with Z′ representing a halogen;
• a nitro, trifluoromethyl or cyano group;
• a (C1-C5)alkyl;
• a (C1-C5)alkyl-X— or (C1-C3)alkyl-X—(C1—C2)alkyl where X represents O, S, SO or SO2;
• a hydroxy(C1-C3)alkyl;
• a CORd or COORd in which Rd is as defined above;
• a methylenedioxy or an ethylenedioxy;
• R8 represents a (C3-C5)cycloalkyl(C1-C3)alkyl;
• or a pharmaceutically acceptable addition salt, hydrate and/or solvate thereof.