System and method for heating the prostate gland to treat and prevent the growth and spread of prostate tumor
AssigneeCelsion Corporation
InventorsAlan J. Fenn, John Mon
Life of this patent
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AssigneeCelsion Corporation
InventorsAlan J. Fenn, John Mon
Estimating the term…
Improvements in safety and efficacy for externally focused adaptive phased array microwave thermotherapy (hyperthermia) for treatment of cancer and benign conditions of an organ or an appendage are described. In order to reduce blood flow thereby accumulating additional equivalent thermal dose following the step of heating an organ or appendage by irradiating microwaves at the organ or appendage, the step of compressing the organ or appendage following the heating step is added to thermotherapy treatment. In a preferred embodiment, the organ is the prostate and periodic prostate compression is employed to reduce the prostate blood flow thereby allowing chemotherapy, thermosensitive liposome-encapsulated chemotherapy, or gene therapy to accumulate in the prostate region during thermotherapy. Doppler ultrasound imaging may be used to measure tumor blood flow rate and then serve as real-time feedback to assist in adjusting the amount of balloon catheter inflation and to assess damage to the tumor vasculature during the treatment.
A method for treating tissue of the prostate comprising the steps of:
A method for safely administering thermotherapy, comprising the steps of:
A method for effectively delivering therapy selected from the group comprising chemotherapy, thermosensitive liposomes containing chemotherapy, and gene therapy comprising the steps of applying one of chemotherapy, thermosensitive liposomes containing chemotherapy, and gene therapy to an organ or an appendage;
A method for effectively delivering liposomes containing chemotherapy to a prostate to be treated comprising the steps of applying energy selected from the group comprising microwave energy, ultrasound energy, laser energy and energy via a fluid to the prostate to be treated;
A method for early treatment of cancerous, pre-cancerous, or benign conditions of a prostate by irradiation of the prostate, comprising the steps of:
Dependencies are inferred from the claim text.