Nucleotide sequence of Escherichia coli pathogenicity islands
AssigneesHuman Genome Sciences, Inc., Wisconsin Alumni Research Foundation
InventorsPatrick J. Dillon, Gil H. Choi, Rodney A. Welch
Life of this patent
Estimating the term…
Abstract
The present invention relates to novel genes located in two chromosomal regions within uropathogenic E. coli that are associated with virulence. These chromosomal regions are known as pathogenicity islands (PAIs). In particular, the present application discloses 142 sequenced fragments (contigs) of DNA from two pools of cosmids covering pathogenicity islands PAI IV and PAI V located on the chromosome of the uropathogenic Escherichia coli J96. Further disclosed are 351 predicted protein-coding open reading frames within the sequenced fragments.
Claims9
An isolated polynucleotide comprising the nucleic acid sequence of ORF ID 4 of Contig ID 65, consisting of nucleotides 2889-1915 at SEQ ID NO:65.
Dependencies are inferred from the claim text.