Back to results
US 6,787,635 B2Granted
Solid phase synthesis supports and methods
Assignee3M Innovative Properties Company
InventorsJerald K. Rasmussen, Larry R. Krepski
Life of this patent
Estimating the term…
Abstract
Functionalized supports and methods for solid phase synthesis. Preferably, the functionalized support is azlactone-functionalized.
Claims34
A functionalized support material having the formula:
- SS—[NH—(C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R1, R2, R3, and R4 are each independently hydrogen or an organic group with the proviso that at least one of R3 and R4 is an aromatic group;
- R7 is hydrogen, a protecting group, or an organic group capable of being derivatized;
- p is at least 1;
- and
- m is 1 to the resin capacity of the support material.
5 more elements
A functionalized support material having the formula:
- SS—[NH—(C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R2, R2, R3, and R4 are each independently hydrogen or an organic group with the proviso that at least one of R3 and R4 is an aromatic group;
- R7 is hydrogen or an organic group;
- p is at least 1:
- and
- m is 1 to the resin capacity of the support material;
- wherein the functionalized support material is in the form of a plurality of particles.
6 more elements
A functionalized support material having the formula:
- SS—[NH—(C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R1, R2, R3, and R4 are each independently hydrogen or an organic group with the proviso that at least one of R3 and R4 is an aromatic group;
- R7 is hydrogen or an organic group;
- p is at least 1:
- and
- m is 1 to the resin capacity of the support material;
- wherein the functionalized support material is in the form of a membrane.
6 more elements
A functionalized support material having the formula;
- SS—[NH—(C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R1, R2, R3, and R4 are each independently hydrogen or an organic group with the proviso that at least one of R3 and R4 is an aromatic group;
- R7 is hydrogen or an organic group;
- p is at least 1;
- and
- m is 1 to the resin capacity of the support material;
- wherein NH—(C(R1)(R2))p—C(R3)(R4)(OR7) is bound to the support material through a carbonyl group.
6 more elements
A functionalized support having the following formula:
- SS—[C(O)—NH—C(R5)(R6)—(CH2)n—C(O)—NH—C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R1, R2, R3, and R4 are each independently hydrogen or an organic group with the proviso that at least one of R3 and R4 is an aromatic group;
- R7 is hydrogen or an organic group;
- R5 and R6 are each independently an organic group;
- n is 0 to 1;
- p is at least 1;
- and
- m is 1 to the resin capacity of the support material.
7 more elements
A functionalized support having the following formula:
- SS—[C(O)—NH—C(R5)(R6)—(CH2)n—C(O)—NH—(R8)—NH—C(O)—R9]m
- wherein:
- SS represents a support material;
- R5, R6, and R9 are each independently an organic group;
- R8 is an organic connecting group;
- n is 0 to 1;
- and
- m is 1 to the resin capacity of the support material.
5 more elements
A functionalized support having the following formula:
- SS—[C(O)—NH—C(R5)(R6)—(CH2)n—C(O)—NH—(C(R1)(R2))p—C(R3)(R4)(OR7)]m
- wherein:
- SS represents a support material;
- R1, R2, R3, and R4 are each independently hydrogen, a (C1-C14)alkyl group, a (C3-C14)cycloalkyl group, or a (C5-C12)aryl group, with the proviso that at least one of R3 and R4 is a (C5-C 12)aryl group;
- R7 is hydrogen or an organic group;
- R5 and R6 are each independently a (C1-C14)alkyl group, a (C3-C14)cycloalkyl group, or a (C5-C 12)aryl group;
- n is 0 to 1;
- p is 1 to 20;
- and
- m is 1 to the resin capacity of the support material.
7 more elements
A functionalized support having the following formula:
- SS—[C(O)—NH—C(R5)(R6)—(CH2)n—C(O)—NH—(R8)—NH—C(O)—R9]m
- wherein:
- SS represents a support material;
- R5and R6 are each independently a(C1-C14)alkyl group, a (C3-C14)cycloalkyl group, or a (C5-C12)aryl group;
- R9 is an organic group;
- R8 is a (C1-C1000)alkylene group;
- n is 0 to 1;
- and
- m is 1 to the resin capacity of the support material.
6 more elements
Dependencies are inferred from the claim text.