Anti-inflammatory compounds derived from Pseudopterorgorgia elisabethae
AssigneesThe Regents of the University of California, Florida Atlantic University Board of Trustees
InventorsRobert S. Jacobs, Russell G. Kerr
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Abstract
Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural formula wherein R1 is a hydrogen, alkyl, aryl, hydroxyalkyl, cycloalkyl, cycloalkenyl, carboxylic acid, alkylamino or amide group having from 2 to 20 carbon atoms, R2, R3, and R4 are each independently hydrogen or an acyl residue having from 1 to 6 carbon atoms, R5 is hydrogen, CH3, or CH2OH, and R6 is an organo group such as a hydrocarbon having from 1 to 10 carbon atoms are disclosed. Other seco-pseudopterosins and compounds related to pseudopterosins are disclosed.
Claims5
A compound of the structural formula:
- wherein R1 is a hydrogen or an alkyl or acyl residue having from 1 to 6 carbon atoms, and R2 is an organo group.
A pharmaceutical composition comprising a therapeutically effective amount of a compound of the structural formula:
- wherein R1, is a hydrogen or an alkyl or acyl residue having from 1 to 6 carbon atoms, and R2 is an organo group, or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient.
Dependencies are inferred from the claim text.