US 6,787,550 B1 · Indole derivatives and their use for the treatment of osteoporosis amongst other applications

Abstract

A compound of formula (1) or a salt thereof, or a solvate thereof, wherein; R1 and R2 each independently represents C1-6alkoxy or halo; R3 and R4 each independently represents hydrogen, C1-6alkoxy, arylC1-6alkoxy, hydroxy, carboxyC1-6alkoxy, hydroxyC1-6alkoxy, dihydroxyC1-6alkoxy, mono- and di-(C1-6alkyl)aminoC1-6alkoxy or aminoC1-6alkoxy, and; R5 represents —NRsRt wherein Rs and Rt each independently represent hydrogen, unsubstituted or substituted C1-6alkyl, or unsubstituted or substituted heterocyclyl, a process for the preparation of such a compound, a pharmaceutical composition containing such a compound and the use of the compound or composition in medicine.

Claims22

Dependent claims

A compound of formula (I)

or a salt thereof, or a solvate thereof,
wherein;
R1 and R2 each independently represents C1-6alkoxy or halo;
R3 and R4 each independently represents hydrogen, C1-6alkoxy, arylC1-6alkoxy, hydroxy, carboxyC1-6alkoxy, hydroxyC1-6alkoxy, dihydroxyC1-6alkoxy, mono- and di-(C1-6alkyl)aminoC1-6alkoxy or aminoC1-6alkoxy and;
R5 represents —NRsRt wherein Rs and Rt each independently represent hydrogen, unsubstituted or substituted C1-6alkyl, or unsubstituted or substituted heterocyclyl.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application

10/018,443Filed 12 Dec 2001

Priority

GB 991437118 Jun 1999

Granted

7 Sep 2004

Term ends

Not estimatedThe source records don’t support an estimate.

Classification27 codes

C07D 209/18
With substituted hydrocarbon radicals attached to carbon atoms of the hetero ring: radicals substituted by carbon atoms having three bonds to…
A61P 1/00
Drugs for disorders of the alimentary tract or the digestive system
A61P 1/04
Drugs for disorders of the alimentary tract or the digestive system: for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of…
A61P 3/06
Drugs for disorders of the metabolism: antihyperlipidemics

Indole derivatives and their use for the treatment of osteoporosis amongst other applications

Life of this patent

Indole derivatives and their use for the treatment of osteoporosis amongst other applications

Life of this patent

Abstract

Claims22