Benzhydryl derivatives

A compound of the formula (I):

• in which R1 and R2 are independently hydrogen, halogen, lower alkoxy, lower alkyl or mono(or di or tri)halo(lower)alkyl,
• R10 is hydrogen or lower alkyl optionally substituted with lower alkoxy, carbamoyl or phenyl,
• R11, R12, R13 and R14 are independently hydrogen, lower alkoxycarbonyl or lower alkyl optionally substituted with hydroxy or lower alkoxy, and
• R10 and R14 optionally forming —(CH2)i—CHR15—(CH2)j—, —(CH2)i—NR16—(CH2)j—, —(CH2)i—O—CH2—CO— or —(CH2)i—O—(CH2)j—, wherein i and j are independently 1 or 2, R15 is hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, amino, lower alkylamino or di(lower)alkylamino and R16 is hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl, benzyloxycarbonyl, lower alkylsulfonyl or mono(or di or tri)halo(lower)alkylsulfonyl, or
• R12 and R13 optionally forming —(CH2)i—CHR15—(CH2)j—, wherein i, j and R15 are defined as above, or
• R13 and R14 optionally forming oxo or two to five methylenes,
• in which R3, R4 and R5 are independently hydrogen;
• halogen;
• lower alkyl, mono(or di or tri)halo(lower)alkyl;
• cyano;
• lower alkoxycarbonyl;
• lower alkylthio;
• lower alkylsulfonyl;
• hydroxy;
• lower alkoxy optionally substituted with lower alkoxy, lower alkoxycarbonyl, carbamoyl, cyano, phenyl or one, two or three halogen(s);
• lower alkenyloxy;
• cyclo(lower)alkyloxy;
• nitro;
• lower alkylamino;
• di(lower)alkylamino;
• or imidazolyl, pyrazolyl, thienyl, thiazolyl, furyl, tetrazolyl, pyridyl or phenyl, each of which may have a substituent selected from a group which consists of lower alkyl, mono(or di or tri)halo(lower)alkyl, lower alkylsulfonyl, lower alkylsulfinyl, lower alkylthio, lower alkylamino and
• di(lower)alkylamino, and
• R6 and R7 are independently hydrogen or halogen, and
• R8 is hydrogen or lower alkyl, and a salt thereof.