Loading patent…
AssigneeTakara Shuzo Co., Ltd.
InventorsMitsuhiro Ueno, Hirofumi Yoshioka, Haruko Konishi, Kimikazu Hashino, Mio Morishita, Hideto Chono, Tsuyoshi Miyamura, Mutsumi Sano, Kiyozo Asada, Kei Fujinaga, Ikunoshin Kato
Estimating the term…
Improved methods for transferring a gene into target cells by using a retrovirus, wherein the gene transfer efficiency is improved and the target cells are efficiently transformed by binding the retrovirus to a functional substance which is immobilized on as carrier and having an activity of binding to retroviruses followed by washing; using an antibody capable of specifically recognizing cells, laminin or mannose-rich type sugar chain as a substance having an activity of binding to the target cells; pre-treating the target cells so as to inactivate transferrin receptor, or introducing a new functional group into the functional substance.
A method for transferring a gene into target cells using a retrovirus, comprising:
The method according to 1, wherein a substrate is used on which the functional substance that binds to the retrovirus and another functional substance that binds to the target cells are immobilized.
A method for transferring a gene into target cells using a retrovirus, comprising:
A method for transferring a gene into target cells using a retrovirus, characterized in that the method comprises infecting target cells with a retrovirus in the presence of two functional substances:
A method for transferring a gene into target cells using a retrovirus, characterized in that the method comprises infecting target cells with a retrovirus in the presence of two functional substances:
Dependencies are inferred from the claim text.