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US 6,787,342 B2Granted
Paste formulations
AssigneeMerial Limited
InventorJun Chen
Life of this patent
Estimating the term…
Abstract
This invention provides for a pharmaceutical or veterinary paste formulation comprising: an effective amount of a therapeutic agent; fumed silica; a viscosity modifier; a hydrophilic carrier; optionally, an absorbent; and optionally, a colorant, stabilizer, surfactant, or preservative. This invention also provides for methods of using these formulations for treating various disease states as well.
Claims9
A pharmaceutical or veterinary paste formulation comprising:
- (a) an effective amount of a Polymorphic B Form of 3-(cyclopropylmethoxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-5H-furan-2-one characterized by the following parameters:
- cristalline system Trigonal space group R-3 description hexagonal unit-cell dimensions a (Å) 18.183 b (Å) 18.183 c (Å) 26.950 α (°) 90 β (°) 90 γ (°) 120 unit-cell volume (Å3) 7716.5 number of molecules per unit-cell Z 18 Temperature of measurement (° K) 293 calculated specific gravity 1.303 weight absorption coefficient (cm−1) 2.11
- (b) a fumed silica;
- (c) a viscosity modifier comprised of two or more functional groups for forming hydrogen bonds on the surface of the fumed silica;
- and
- (d) a carrier.
3 more elements
Dependencies are inferred from the claim text.