Diagnosis of premature ovarian failure
AssigneeAuckland Uniservices Limited
InventorAndrew N. Shelling
Life of this patent
Estimating the term…
Abstract
Methods by which a predisposition to Premature Ovarian failure (POF) can be determined. In particular, methods are provided for detecting whether a female has a predisposition to POF with reference to an alteration (mutation) in the gene coding inhibin.
Claims7
A method of testing to detect whether a human female subject is predisposed to Premature Ovarian Failure (POF), the method comprising at least a step of detecting the nucleotide present at position 769 of the gene encoding inhibin alpha in said subject, wherein the presence of an A at said position is indicative of a predisposition to POF.
A method of testing to detect whether a human female subject is predisposed to Premature Ovarian Fallure (POF), the method comprising at least a step of detecting the amino acid present at position 257 of inhibin alpha, wherein the presence of threonine at said position is indicative of a predisposition to POF.
Dependencies are inferred from the claim text.