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US 6,787,141 B1Granted
Peptide having for fibrinogen fragment E activity, analogs, antibodies and uses thereof
AssigneeThe University Court of the University of Aberdeen
InventorsWilliam Thomas Melvin, William Douglas Thompson, Christina Maureen Stirk
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Abstract
Fibrin degradation products stimulate cell proliferation and angiogenesis. The present invention provides peptides, analogs, and antibodies which are useful in the modulation of binding fibrin fragment E to cell receptors and the modulation of such activity.
Claims3
A peptide consisting of an amino acid sequence selected from the group consisting of:
- CRAHSFGSPRPLPVV (SEQ ID NO:1),
- SRAHSFGSPRPLPVV (SRQ ID NO:2), and
- CRAHSFVSPRPLPVV (SEQ ID NO:3)
- said peptide being effective to bind a fibrin fragment E binding site, thereby stimulating fibrin fragment E activity.
1 more element
Dependencies are inferred from the claim text.