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US 6,784,315 B2Granted
Stilbene derivative crystal and method for producing the same
AssigneeAjinomoto Co., Inc.
InventorsShinichiro Takahashi, Yoko Sugawara, Hiroyuki Matsueda
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AssigneeAjinomoto Co., Inc.
InventorsShinichiro Takahashi, Yoko Sugawara, Hiroyuki Matsueda
Estimating the term…
A Type IV crystal of (Z)-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)vinyl]phenyl]-L-serinamide hydrochloride, which can be produced by crystallization using a solvent containing water at 2% by weight at the maximum and which has a X ray powder diffraction pattern containing peaks at least at 13.4°, 18.7°, 19.4°, and 22.5° (2θ), is provided. This compound is useful as an effective ingredient for a carcinostatic agent. The crystal of the present invention has excellent properties desirable from the standpoint of the production of medicinal products, i.e., reduced water adsorption and extremely high stability to water. Also provided are a method for producing the Type IV crystal thereof and a method for use of the crystal.
A Type IV crystal of (Z)-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)vinyl]phenyl]-L-serinamide hydrochloride, which has a X ray powder diffraction pattern which has peaks at least at 13.4°, 18.7°, 19.4°, and 22.5° (2θ).
Dependencies are inferred from the claim text.